Step by Step

INTRODUCTION

ABIM MOC Activity ID

4/18/2017 - Medical Grand Rounds: Experience with allogeneic transplant for sickle cell disease

QUIZ

EVALUATION

CERTIFICATE

INTRODUCTION

Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Recognize why clinical trial participation is important for developing therapies for SCD.
  • Recognize what the current landscape is for bone marrow transplantation strategies in SCD.
  • Describe what are the prospects for novel curative gene therapy approaches based upon bone marrow transplantation.

Suggested Additional Reading:

  1. Uchida, Hargrove, et al., Mol Ther, 20(10), 1882-92, 2012.
  2. Uchida, Washington, et al., J Virol, 83(19), 9854-9862, 2009.
  3. Pawliuk R, Westerman KA, Fabry ME, et al. Correction of sickle cell disease in transgentic mouse models by gene therapy. Science 294, 2001.

Authors:
John F. Tisdale, MD — Senior Investigator, Molecular and Clinical Hematology Branch National Heart, Lung, and Blood Institute
No relationships with industry relevant to the content of this educational activity have been disclosed.
No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

This activity is approved for AMA PRA Category 1 Credit™

The University of Pittsburgh is an affirmative action, equal opportunity institution.