Step by Step


ABIM MOC Activity ID

4/18/2017 - Medical Grand Rounds: Experience with allogeneic transplant for sickle cell disease





Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Recognize why clinical trial participation is important for developing therapies for SCD.
  • Recognize what the current landscape is for bone marrow transplantation strategies in SCD.
  • Describe what are the prospects for novel curative gene therapy approaches based upon bone marrow transplantation.

Suggested Additional Reading:

  1. Uchida, Hargrove, et al., Mol Ther, 20(10), 1882-92, 2012.
  2. Uchida, Washington, et al., J Virol, 83(19), 9854-9862, 2009.
  3. Pawliuk R, Westerman KA, Fabry ME, et al. Correction of sickle cell disease in transgentic mouse models by gene therapy. Science 294, 2001.

John F. Tisdale, MD — Senior Investigator, Molecular and Clinical Hematology Branch National Heart, Lung, and Blood Institute
No relationships with industry relevant to the content of this educational activity have been disclosed.
Authors disclosure of relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients is listed above. No other planners, members of the planning committee, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits. Each physician should only claim credit commensurate with the extent of their participation in the activity.

The University of Pittsburgh is an affirmative action, equal opportunity institution.