Step by Step


ABIM MOC Activity ID

5/16/2017- Medical Grand Rounds: Medical Devices Bench to Bedside





Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Review recent studies of CPAP therapy that investigated adherence.
  • Explain how PAP therapy when used consistently results in decreased daytime sleepiness, improved HRQOL, and decreased vascular risk.
  • Describe how interstitial fluid glucose sensing, computer algorithms for determination of insulin and glucagon dosing, and pumps for subcutaneous drug delivery can be combined to create an automated, bionic pancreas.
  • Explain how glucagon contributes to glucose control in a bi-hormonal bionic endocrine pancreas.
  • Describe the performance of the bionic pancreas in outpatient, home use studies and recognize the steps that remain in demonstrating the safety and effectiveness of a bionic pancreas, including a pivotal trial agreed with the FDA.

Suggested Additional Reading:

  1. Sleep 2011, 34:303-314
  2. Sleep 2012, 35:757-767
  3. Strohl et al, Resp Investigation. 2016,54:241-249.
  4. Russell and El-Khatib, et al. (2014) New Eng J Med. 371:313.
  5. El-Khatib and Russell, et al. (2010) Sci Trans Med. 2:27ra27
  6. Woodson et al. Otolaryngol Head Neck Surg. 2016, 154:181-8.

Patrick J Strollo Jr, MD, FCCP, FAASM — Vice Chair of Medicine for Veterans Affairs Professor of Medicine and Clinical and Translational Science Division of Pulmonary, Allergy, and Critical Care Medicine
Dr. Strollo receives grant/research funding from the Federal Government, Philips-Respironics, Inc., ResMed, Corp., Inspire Medical Systems, National Football League, PinMed. He is an Industry Advisory for ResMed, Emmi Solutions, Jazz Pharmaceuticals, Itamar Medical, Inspire Medical Systems, Separation Design Group. He is a consultant for Inspire Medical Systems.
Steven J. Russell, MD, PhD — Assistant Professor of Medicine, Harvard Medical School Assistant Physician, Internal Medicine, Massachusetts General Hospital
Dr. Russell receives grant/research support from Zealand Pharma. He is a consultant with Flexion Therapeutics and Tandem Diabetes Care. He is a stockholder with Companion Medical and receives honoraria for lectures from Sanofi Aventis, Lilly, Dexcom, Novo Nordisk, In-kind support from (donated or loaned materials): Eli Lilly, SweetSpot Diabetes/Dex.
No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

The University of Pittsburgh is an affirmative action, equal opportunity institution.