Step by Step


ABIM MOC Activity ID

5/16/2017- Medical Grand Rounds: Medical Devices Bench to Bedside





Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Review recent studies of CPAP therapy that investigated adherence.
  • Explain how PAP therapy when used consistently results in decreased daytime sleepiness, improved HRQOL, and decreased vascular risk.
  • Describe how interstitial fluid glucose sensing, computer algorithms for determination of insulin and glucagon dosing, and pumps for subcutaneous drug delivery can be combined to create an automated, bionic pancreas.
  • Explain how glucagon contributes to glucose control in a bi-hormonal bionic endocrine pancreas.
  • Describe the performance of the bionic pancreas in outpatient, home use studies and recognize the steps that remain in demonstrating the safety and effectiveness of a bionic pancreas, including a pivotal trial agreed with the FDA.

Suggested Additional Reading:

  1. Sleep 2011, 34:303-314
  2. Sleep 2012, 35:757-767
  3. Strohl et al, Resp Investigation. 2016,54:241-249.
  4. Russell and El-Khatib, et al. (2014) New Eng J Med. 371:313.
  5. El-Khatib and Russell, et al. (2010) Sci Trans Med. 2:27ra27
  6. Woodson et al. Otolaryngol Head Neck Surg. 2016, 154:181-8.

Patrick J Strollo Jr, MD, FCCP, FAASM — Vice Chair of Medicine for Veterans Affairs Professor of Medicine and Clinical and Translational Science Division of Pulmonary, Allergy, and Critical Care Medicine
Dr. Strollo receives grant/research funding from the Federal Government, Philips-Respironics, Inc., ResMed, Corp., Inspire Medical Systems, National Football League, PinMed. He is an Industry Advisory for ResMed, Emmi Solutions, Jazz Pharmaceuticals, Itamar Medical, Inspire Medical Systems, Separation Design Group. He is a consultant for Inspire Medical Systems.
Steven J. Russell, MD, PhD — Assistant Professor of Medicine, Harvard Medical School Assistant Physician, Internal Medicine, Massachusetts General Hospital
Dr. Russell receives grant/research support from Zealand Pharma. He is a consultant with Flexion Therapeutics and Tandem Diabetes Care. He is a stockholder with Companion Medical and receives honoraria for lectures from Sanofi Aventis, Lilly, Dexcom, Novo Nordisk, In-kind support from (donated or loaned materials): Eli Lilly, SweetSpot Diabetes/Dex.
Authors disclosure of relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients is listed above. No other planners, members of the planning committee, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits. Each physician should only claim credit commensurate with the extent of their participation in the activity.

The University of Pittsburgh is an affirmative action, equal opportunity institution.