Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

Review oral therapy for Endocarditis
Discuss HCV infected to uninfected solid organ transplants
Examine therapy for ESBL infections, ESBL and travel
Explain latent TB therapy, and prednisone with ART in TB
Review FDA approved new antibiotics
Review old antibiotic, with new FDA warning

Suggested Additional Reading:

Meintjes G, et al. N Engl J Med 2018; 379:1915-1925
Lai RP, et al. HIV-1 tuberculosis-associated immune reconstitution inflammatory syndrome. Semin Immunopathol 2016;38:185-198.
Uthman OA, et al. Optimal timing of antiretroviral therapy initiation for HIV-infected adults with newly diagnosed pulmonary tuberculosis: a systematic review and meta-analysis. Ann Intern Med 2015;163:32-39.
Marais BJ, et al. The natural history of childhood intra-thoracic tuberculosis: a critical review of literature from the pre-chemotherapy era. Int J Tuberc Lung Dis. 2004 Apr;8(4):392-402
Comstock GW, et al. Tuberculosis morbidity in the US Navy: its distribution and decline. Am Rev Respir Dis. 1974;110(5):572.
Comstock GW. How much isoniazid is needed for prevention of tuberculosis among immunocompetent adults? Int J Tuberc Lung Dis. 1999;3(10):847
Lewinsohn DM, et al. Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnostics of Tuberculosis in Adults and Children. Clin Infect Dis 2017:64:111.
Hilty M, et al. Transmission dynamics of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the tertiary care hospital and the household setting. Clin Infect Dis 2012; 55: 967–75.
Nemeth J, et al. Multidrug-resistant bacteria in travellers hospitalized abroad: prevalence, characteristics, and influence on clinical outcome. J Hosp Infect 2012; 82: 254–9.

Authors:

Carolyn Fernandes, MD — Division of Infectious Diseases Clinical Assistant Professor of Medicine Director, CCID Travel Clinic University of Pittsburgh Medical Center (UPMC)
No relationships with industry relevant to the content of this educational activity have been disclosed.

No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

This activity is approved for AMA PRA Category 1 Credit™

The University of Pittsburgh is an affirmative action, equal opportunity institution.