Step by Step


ABIM MOC Activity ID

3/26/2019 - Medical Grand Rounds: Gastroenterology, Hepatology and Nutrition Year in Review





Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Identify indications for PPI use, including the AspECT trial data and the SUP-ICU trial data.
  • Evaluate articles published in the past year dealing with PPI safety related to risk of dementia, bone fracture, and kidney disease in the context of previous published literature.
  • Determine the risk of reactivation of Hepatitis C therapy during chemotherapy
  • Realize the relative risk associated with the long term use of the older formulation of tenofovir (TDF) vs the newer formulation (TAF)
  • Evaluate the proposed risk score for HE in cirrhosis

Suggested Additional Reading:

  1. Jankowski JAZ, de Caestecker J, Love SB, et al. Esomeprazole and aspirin in Barrett's oesophagus (AspECT) a randomized factorial trial. Lancet. 2018 Aug 4;392(10145):400-408. doi: 10.1016/S0140-6736(18)31388-6. Epub 2018 Jul 26.
  2. Krag M, Marker S, Perner A, et al. Pantoprazole in Patients in Risk for Gastrointestinal Bleeding in the ICU. N Engl J Med 2018; 379:2199-2208. DOI: 10.1056/NEJMoa1714919
  3. Gromm, et al. JAMA Neurol. 2016 Apr;73(4):410-6.
  4. Kamal, et al. J Clin Gastroenterol 2018;52:468–476
  5. Tapper EB, Parikh ND, Sengupta N, et al. A risk score to predict the development of hepatic encephalopathy in a population-based cohort of patients with cirrhosis. Hepatology. 2018 Oct;68(4):1498-1507. doi: 10.1002/hep.29628. Epub 2018 May 14.
  6. Agarwal K, Brunetto M, Seto WK, et al. 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection.J Hepatol. 2018 Apr;68(4):672-681. doi: 10.1016/j.jhep.2017.11.039. Epub 2018 Jan 17.

Kenneth Fasanella, MD — Assistant Professor of Medicine Program Director, Gastroenterology Fellowship Division of Gastroenterology, Hepatology and Nutrition
Dr. Fasanella is a consultant with Lygenesis, Inc.
Naudia Jonassaint, MD, MHS — Assistant Professor of Medicine Medical Director, Hepatology, Division of Gastroenterology, Hepatology and Nutrition Vice Chair for Diversity and Inclusion, Department of Medicine
No relationships with industry relevant to the content of this educational activity have been disclosed.
No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

The University of Pittsburgh is an affirmative action, equal opportunity institution.