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INTRODUCTION

ABIM MOC Activity ID

11/24/2020 - Medical Grand Rounds: Special K-Club Series

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EVALUATION

CERTIFICATE

INTRODUCTION

Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Develop, validate, and apply a metric that will characterize specific low-value prescribing practices using administrative data and that reflects the perspectives of patients, prescribers, and payers as they relate to health care value.
  • Describe the effects of early enteral nutrients on inflammation and metabolism in sepsis
  • Review the evolutionary stress of maintaining serum [K+]
  • Reveal the role of KS-WNK1 in cells, in animals, and in phase transitions

Suggested Additional Reading & Joint Accreditation Statement: Note: This Accreditation Statement Supersedes All Other Statements:

Suggested additional reading:

  1. Pickering AN, Radomski TR, J Am Geriatr Soc 2020
  2. Radomski TR, JAMA Network Open 2020
  3. Radomski TR, J Am Geriatr Soc 2019
  4. Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Nkashama L, Namboodiri H, Xie J, McClain K, Marciszyn A, Kleyman T, Tan R, Stolz D, Puthenveedu M, Huang CL, Subramanya AR. Potassium-Regulated Distal Tubule WNK Bodies are Kidney-Specific WNK1 Dependent. Mol Biol of the Cell. 2018. PMID: 29237822.
  5. Boyd-Shiwarski CR, Subramanya AR. The renal response to potassium stress: Integrating past with present. Current Opinion in Nephrology and Hypertension. 2017. PMID: 28614118.
  6. Shin T, Brangqynne CP. Liquid phase condensation in cell physiology and disease. Science. 2017. PMID 28935776.
  7. Taylor, BE; McClave, SA; Martindale, RG; et al. Critical Care Medicine: February 2016 - Volume 44 - Issue 2 - p 390-438.
  8. Shah FA, Mahmud H, Gallego-Martin T, Jurczak MJ, O'Donnell CP, McVerry BJ. Therapeutic Effects of Endogenous Incretin Hormones and Exogenous Incretin-Based Medications in Sepsis. J Clin Endocrinol Metab. 2019 Nov 1;104(11):5274-5284. doi: 10.1210/jc.2019-00296. PMID: 31216011; PMCID: PMC6763279.
  9. Shah FA, Kitsios GD, Zhang Y, Morris A, Yende S, Huang DT, O'Donnell CP, McVerry BJ. Rationale for and Design of the Study of Early Enteral Dextrose in Sepsis: A Pilot Placebo-Controlled Randomized Clinical Trial. JPEN J Parenter Enteral Nutr. 2020 Mar;44(3):541-547. doi: 10.1002/jpen.1608. Epub 2019 May 30. PMID: 31148210; PMCID: PMC6884652.


Joint Providership Statement: 
In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit[s]™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This educational activity is approved for 1.0 contact hours.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

Authors:
Cary Boyd-Shiwarski, MD, PhD — Assistant Professor of Medicine, Division of Renal-Electrolyte, University of Pittsburgh
Dr. Boyd-Shirwarski is a Consultant for Sanofi-Genzyme.
Faraaz Shah, MD, MPH — Assistant Professor of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh
Dr. Shah receives Grant/Research support from NIH and is a recipient of a Nestlé Nutrition Institute Clinical Nutrition Fellowship for Physicians.
Thomas Radomski, MD, MS — Assistant Professor of Medicine and Clinical & Translational Science Division of General Internal Medicine, University of Pittsburgh
No relationships with industry relevant to the content of this educational activity have been disclosed.
Authors disclosure of relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients is listed above. No other planners, members of the planning committee, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits. Each physician should only claim credit commensurate with the extent of their participation in the activity.

The University of Pittsburgh is an affirmative action, equal opportunity institution.