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INTRODUCTION

9/22/2022 Anesthesiology Grand Rounds - Perioperative Neurocognitive disorders - the mechanistic insights

QUIZ

EVALUATION

CERTIFICATE

INTRODUCTION

Credit Hours: CME 1.00

Target Audience:

Anesthesiologists and anesthesiologists-in-training and other anesthesia professionals, nurse anesthetists and anesthesia assistants.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Recognize what is perioperative neurocognitive disorders.
  • Describe the consequences of periperative neurocognitive disorders.
  • Identify Alzheimer’s disease pathogenesis
  • Discuss the mechanism of periperative neurocognitive disorders.
  • Describe the potential interventions of perioperative neurocognitive disorders.

Suggested Additional Reading & Joint Accreditation Statement - Note: This Accreditation Statement Supersedes All Other Statements:

Suggested Additional Reading

  1. Vutskits, L. and Xie, Z. Lasting impact of general anesthesia on the brain: from molecular mechanisms to functional relevance. Nature Review Neuroscience. 2016, November, (17): 705-717.
  2. Eckenhoff RG, Maze M, Xie Z, Culley DJ, Goodlin SJ, Zuo Z, Wei H, Whittington RA, Terrando N, Orser BA, Eckenhoff MF. Perioperative Neurocognitive Disorder: State of the Preclinical Science. Anesthesiology, 2020 Jan;132(1):55-68.
  3. Liang, F., Baldyga, K., Quan, Q., Khatri, A., Choi, S., Wiener-Kronish, J., Akeju, O., Westover, B.M., Cody, K., Shen, Y., Marcantonio, E.R., Xie, Z. Preoperative Plasma Tau-PT217 and Tau-PT181 Are Associated with Postoperative Delirium. Annals of Surgery. Online ahead of print.
  4. Zhang, C., Han, Y., Liu, X., Tan, H., Dong, Y., Zhang, Y., Liang, F., Zheng, H., Crosby, G., Culley, D., Marcantonio, ER., Shen, Y., Cao, J., and Xie, Z. Odor enrichment attenuates the anesthesia/surgery-induced cognitive impairment. Annals of Surgery. Online ahead of print.


Joint Accreditation Statement:

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


The University of Pittsburgh School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Each physician should only claim credit commensurate with the extent of their participation in the activity. 


Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

Authors:
Zhongcong Xie, MD, PhD, FASA — Henry K. Beecher Professor of Anesthesia, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School
Dr. Xie receives grant/research support from National Institutes of Health and is a Consultant for Baxter (invited speaker), Shanghai 9th and 10th hospital
No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

This activity is approved for AMA PRA Category 1 Credit™

The University of Pittsburgh is an affirmative action, equal opportunity institution.