Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Abstract
This series highlights practice-changing updates in various medical fields, and in this session we will be hearing from some of our experts in Geriatric Medicine. Review the current prevalence of dementia and medical trials to treat individuals 65 or older.

Upon completion of this activity, participants should be able to:

• Be prepared to address questions from patients and families about the specificity of biomarkers in diagnosing Alzheimer disease.
• Build competency to address questions from patients and families about the specificity of biomarkers in diagnosing Alzheimer disease
• Describe the contribution of social, behavioral, environmental and vascular risk factors to the development of dementia, as well as the sensitivity periods over the life course when interventions may have the largest impact on risk reduction.
• Identify the key features of delirium in hospitalized older adults in order to improve detection and initiative interventions.

Suggested Additional Reading

1. Luckett PH, Chen C, Gordon BA, Wisch J, Berman SB, Chhatwal JP, Cruchaga C, Fagan AM, Farlow MR, Fox NC, Jucker M, Levin J, Masters CL, Mori H, Noble JM, Salloway S, Schofield PR, Brickman AM, Brooks WS, Cash DM, Fulham MJ, Ghetti B, Jack CR Jr, Vöglein J, Klunk WE, Koeppe R, Su Y, Weiner M, Wang Q, Marcus D, Koudelis D, Joseph-Mathurin N, Cash L, Hornbeck R, Xiong C, Perrin RJ, Karch CM, Hassenstab J, McDade E, Morris JC, Benzinger TLS, Bateman RJ, Ances BM; Dominantly Inherited Alzheimer Network (DIAN). Biomarker clustering in autosomal dominant Alzheimer's disease. Alzheimers Dement. 2022 Apr 1:10.1002/alz.12661. doi: 10.1002/alz.12661. Epub ahead of print. PMID: 35362200; PMCID: PMC9525451.
2. Lee M, Whitsel E, Avery C, Hughes TM, Griswold ME, Sedaghat S, Gottesman RF, Mosley TH, Heiss G, Lutsey PL. Variation in Population Attributable Fraction of Dementia Associated With Potentially Modifiable Risk Factors by Race and Ethnicity in the US. JAMA Netw Open. 2022 Jul 1;5(7):e2219672. doi: 10.1001/jamanetworkopen.2022.19672. PMID: 35793088; PMCID: PMC9260480.
3. Marcantonio E, et al. Comparative Implementation of a Brief App-directed Delirium Identification Protocol by Hospitalists, Nurses, and Nursing Assistants. Ann Intern Med. 2022 January; 175(1): 65-73. doi: 10.7326/M21-1687.

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit[s]™. Physicians should only claim credit commensurate with the extent of their participation in the activity. This educational activity is approved for 1.0 contact hours.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.