Credit Hours: CME 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Genomics and epigenomics of bone and soft tissue tumors
Benjamin Nacev, MD, PhD
Assistant Professor of Medicine
Division of Hematology/Oncology

Mitochondrial biogenesis in macrophages exacerbates inflammation in atherosclerosis
Niranjana Natarajan, MD, PhD
Postdoctoral Associate
Division of Cardiology/VMI

Hypomorphic NOTCH1 expression and its phenotypic correlation to cardiomyocytes in congenital heart disease
Anita Saraf, MD, PhD
Assistant Professor of Medicine
Division of Cardiology

Educational Objectives:

Upon completion of this activity, participants should be able to:

Describe how complex mutations contribute to congenital heart disease.
Explain how NOTCH1 mutations contribute to cardiomyocyte dysfunction
Identify how finding novel therapies for NOTCH1 dependent HLHS
Recognize the heterogenity of genetics events in sarcomas

Suggested Additional Reading & Joint Accreditation Statement - Note: This Accreditation Statement Supersedes All Other Statements:

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME) and the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit[s]™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

Authors:

Anita Saraf, MD, PhD — Assistant Professor of Medicine, Division of Cardiology, University of Pittsburgh
No relationships with industry relevant to the content of this educational activity have been disclosed.

Benjamin Nacev, MD, PhD — Assistant Professor of Medicine, Division of Hematology/Oncology, University of Pittsburgh
No relationships with industry relevant to the content of this educational activity have been disclosed.

Niranjana Natarajan, MD, PhD — Postdoctoral Associate, Division of Cardiology/VMI, University of Pittsburgh
No relationships with industry relevant to the content of this educational activity have been disclosed.

No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

This activity is approved for AMA PRA Category 1 Credit™

The University of Pittsburgh is an affirmative action, equal opportunity institution.