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INTRODUCTION

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10/03/2023 - Medical Grand Rounds: Biological rhythms in health and disease: discovery of new non-circadian 12-hour rhythms in mice and humans

QUIZ

EVALUATION

CERTIFICATE

INTRODUCTION

Credit Hours: 1.00

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

    • Describe the importance of biological rhythms in human health. 
    • Identify the different kinds of biological rhythms including circadian and ultradian rhythms
    • Explain the conservation of 12 hour ultradian rhythms from marine mammals to humans

Suggested Additional Reading:

  1. Cederroth, C.R., Albrecht, U., Bass, J., Brown, S.A., Dyhrfjeld-Johnsen, J., Gachon, F., Green, C.B., Hastings, M.H., Helfrich-Förster, C., Hogenesch, J.B., et al. (2019). Medicine in the Fourth Dimension. Cell Metabolism 30, 238-250. https://doi.org/10.1016/j.cmet.2019.06.019.
  2. Ballance, H., and Zhu, B. (2021). Revealing the hidden reality of the mammalian 12-h ultradian rhythms. Cellular and Molecular Life Sciences. 10.1007/s00018-020-03730-5.
  3. Bass, J., and Lazar, M.A. (2016). Circadian time signatures of fitness and disease. Science 354, 994-999. doi:10.1126/science.aah4965.

Authors:
Bokai Zhu, PhD — Assistant Professor of Medicine, Division of Endocrinology, University of Pittsburgh School of Medicine
No planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
Matthew Steinhauser, MD — Associate Professor of Medicine, Division of Cardiology, University of Pittsburgh School of Medicine
No planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Pittsburgh School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

The University of Pittsburgh is an affirmative action, equal opportunity institution.