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INTRODUCTION

ABIM MOC Activity ID

1/23/2024 - Medical Grand Rounds: Bacteriophage: The Next Generation of Antimicrobial Agents

QUIZ

EVALUATION

CERTIFICATE

INTRODUCTION

Credit Hours: CME 0.75

Target Audience:

Faculty, residents, fellows, and community physicians in General Internal Medicine and subspecialties.

Educational Objectives:

Upon completion of this activity, participants should be able to:

    • Describe the current landscape of and experience experience with bacteriophage therapy, including at UPMC
    • Evaluate the interactions between phages, bacteria, and the human host, in patients treated with phages
    • Explore the current research and clinical trial landscape to bring phages to the mainstream

Suggested Additional Reading & Joint Accreditation Statement - Note: This Accreditation Statement Supersedes All Other Statements:

Suggested Additional Reading:

  • Suh, GA et al. Considerations for the Use of Phage Therapy in Clinical Practice. Antimicrob Agents Chemother . 2022 Mar 15;66(3):e0207121.
  • Haidar, G et al [...] Van Tyne, D. Phage therapy in a lung transplant recipient with cystic fibrosis infected with multidrug-resistant Burkholderia multivorans. Transpl Infect Dis . 2023 Apr;25(2):e14041.  doi: 10.1111/tid.14041.
  • Stellfox M, et al [...] Van Tyne, D. Bacteriophage and antibiotic combination therapy for recurrent Enterococcus faecium bacteremia. mBio, 2024, In Press.
  • Nordstrom R, et al [...] Van Tyne, D. Genomic characterization of lytic bacteriophages targeting genetically diverse Pseudomonas aeruginosa clinical isolates. iScience . 2022 May 10;25(6):104372.  doi: 10.1016/j.isci.2022.104372.  eCollection 2022 Jun 17.
  • Dedrick R, et al, Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease. Clin Infect Dis . 2023 Jan 6;76(1):103-112.  doi: 10.1093/cid/ciac453.

Joint Accreditation Statement

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


Physician (CME)

The University of Pittsburgh School of Medicine designates this enduring material activity for a maximum of 0.75 AMA PRA Category 1 Credits™.Each physician should only claim credit commensurate with the extent of their participation in the activity.


Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

Authors:
Daria Van Tyne, PhD — Assistant Professor of Medicine, Division of Infectious Diseases, Chair, Phage Biology Working Group, Pittsburgh Phage Project (P3) University of Pittsburgh
No planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.
Ghady Haidar, MD — Assistant Professor of Medicine, Transplant Infectious Diseases Program, Chair, Clinical Phage Therapy Working Group, Pittsburgh Phage Project (P3), University of Pittsburgh and UPMC
Dr. Haidar receives grant/research support from NIH, Allovir, Karius, Regeneron, the Cystic Fibrosis Foundation, and AstraZeneca. He is a consultant for Karius, AstraZeneca, and SNIPR BIOME. Dr. Haidar received honoraria from MDOutlook, PeerView Institute for Medical Education, and PRIME Inc.
No other members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

This activity is approved for AMA PRA Category 1 Credit™

The University of Pittsburgh is an affirmative action, equal opportunity institution.